High Potency Triple Retinol Renewal Serum vs Super Saturated Hydrating Barrier Serum with 30% Glycerin + Polyglutamic Acid — Ingredient Comparison

Perricone MD

High Potency Triple Retinol Renewal Serum

Serum · 50 ingredients

Perricone MD High Potency Triple Retinol Renewal Serum works day and night to visibly reduce lines, wrinkles & uneven texture.

Experiment

Super Saturated Hydrating Barrier Serum with 30% Glycerin + Polyglutamic Acid

Serum · 20 ingredients

A hydrating serum formulated for dry, combination, and normal skin types, with a focus on reinforcing the skin barrier and relieving dryness. A high concentration of glycerin delivers fast, lasting hydration while supporting the barrier, and polyglutamic acid works at the skin's surface to create a plump, dewy appearance. Prickly pear extract helps calm reactive skin and defend against irritation, while niacinamide rounds out the formula with additional barrier-supporting benefits.

Fragrance-free

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How these two interact

No conflicts — safe to layer

Both are Serum products.

At a glance

Fragrance-free

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Price

$135

$28

$107 less

Key ingredients

Retinol

A retinoid that speeds cell turnover to smooth texture, soften lines, and clear pores.

L-Ascorbic Acid

A form of vitamin C — an antioxidant that brightens, fades dark spots, and supports collagen.

Niacinamide

Strengthens the barrier, controls oil, and fades dark spots — gentle and plays well with almost everything.

Hyaluronic Acid

Holds water in the skin for instant plumping and hydration.

AHA

A water-soluble acid that exfoliates the surface for smoother, brighter, more even skin.

Ceramides

Barrier lipids that seal in moisture and repair a compromised skin barrier.

Peptides

Amino-acid messengers that signal collagen production for firmer, smoother skin.

Squalane

A lightweight, biomimetic oil that softens without clogging pores — pairs perfectly with strong actives to offset dryness.

Glycerin

The workhorse humectant — simple, effective, and exceptionally well-tolerated.

Rubus Idaeus (Raspberry) Seed Oil

A nourishing plant oil that softens skin and helps seal in moisture.

Allantoin

Calms redness and smooths texture — buffers harsh actives beautifully.

Bisabolol

A soothing ingredient that calms redness and irritation.

Vitamin E

An antioxidant that protects the barrier and supercharges vitamin C.

Glycine Soja (Soybean) Oil

A nourishing plant oil that softens skin and helps seal in moisture.

30% Glycerin

The workhorse humectant — simple, effective, and exceptionally well-tolerated.

Polyglutamic Acid

Holds even more water than hyaluronic acid and forms a moisture-locking film on the surface.

Glycerin

The workhorse humectant — simple, effective, and exceptionally well-tolerated.

Niacinamide

Strengthens the barrier, controls oil, and fades dark spots — gentle and plays well with almost everything.

Squalane

A lightweight, biomimetic oil that softens without clogging pores — pairs perfectly with strong actives to offset dryness.

Allantoin

Calms redness and smooths texture — buffers harsh actives beautifully.

Bisabolol

A soothing ingredient that calms redness and irritation.

Vitamin E

An antioxidant that protects the barrier and supercharges vitamin C.

What it targets

Hydration

Barrier

Brightening

Anti-aging

Firmness

Texture

Acne

Pores

Oil control

Soothing

Antioxidant

Healing

Hydration

Barrier

Brightening

Texture

Pores

Oil control

Soothing

Antioxidant