5 PDRN Collagen Intense Vitalizing Serum with Adenosine & Niacinamide

5 PDRN Collagen Intense Vitalizing Serum with Adenosine & Niacinamide

Total RF Serum Anti-Wrinkle Face Serum

Total RF Serum Anti-Wrinkle Face Serum

5 PDRN Collagen Intense Vitalizing Serum with Adenosine & Niacinamide

COSRX

5 PDRN Collagen Intense Vitalizing Serum with Adenosine & Niacinamide

Serum · 39 ingredients · South Korea

COSRX 5 PDRN Collagen Intense Vitalizing Serum lifts, firms, and brightens with five PDRN derivatives and low-molecular collagen. Clinically proven to boost radiance and smooth fine lines.

Total RF Serum Anti-Wrinkle Face Serum

RODAN + FIELDS

Total RF Serum Anti-Wrinkle Face Serum

Serum · 50 ingredients

Rodan + Fields Total RF Serum Anti-Wrinkle Face Serum is a comprehensive anti-aging serum that energizes millions of surface skin cells by 200% to address key signs of skin aging.

Cruelty-free
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How these two interact

No conflicts — safe to layer

Both are Serum products.

At a glance
Cruelty-free
Price
$20
$140 less
$160
Key ingredients

Niacinamide

Strengthens the barrier, controls oil, and fades dark spots — gentle and plays well with almost everything.

Hyaluronic Acid

Holds water in the skin for instant plumping and hydration.

Peptides

Amino-acid messengers that signal collagen production for firmer, smoother skin.

Centella

Calms inflammation and speeds barrier recovery.

Vitamin E

An antioxidant that protects the barrier and supercharges vitamin C.

Glycerin

The workhorse humectant — simple, effective, and exceptionally well-tolerated.

Panthenol (B5)

A barrier-repairing humectant that hydrates and calms — a sensitive-skin staple.

Adenosine

A cell-signaling ingredient that smooths fine lines and supports firmer skin.

Collagen

A large hydrating molecule that forms a moisture-retaining film on the surface for a plump, smooth feel.

Allantoin

Calms redness and smooths texture — buffers harsh actives beautifully.

Alpha Arbutin

A safe, stable brightener without the risks of hydroquinone.

Niacinamide

Strengthens the barrier, controls oil, and fades dark spots — gentle and plays well with almost everything.

Peptides

Amino-acid messengers that signal collagen production for firmer, smoother skin.

Centella

Calms inflammation and speeds barrier recovery.

Squalane

A lightweight, biomimetic oil that softens without clogging pores — pairs perfectly with strong actives to offset dryness.

Vitamin E

An antioxidant that protects the barrier and supercharges vitamin C.

Glycerin

The workhorse humectant — simple, effective, and exceptionally well-tolerated.

Adenosine

A cell-signaling ingredient that smooths fine lines and supports firmer skin.

Hyaluronic Acid

Holds water in the skin for instant plumping and hydration.

Panthenol (B5)

A barrier-repairing humectant that hydrates and calms — a sensitive-skin staple.

Rice Extract

A rice-derived ingredient that brightens and softens for a smooth, even glow.

What it targets

Hydration

Barrier

Brightening

Anti-aging

Firmness

Texture

Pores

Oil control

Soothing

Antioxidant

Healing

Hydration

Barrier

Brightening

Anti-aging

Firmness

Pores

Oil control

Soothing

Antioxidant

Healing